To find out whether a substance is carinogenetic go to
"http://ntp-server.niehs.nih.gov/" and click
on "Testing Status of Agents at NTP".
Levels:
- CE = clear evidence
- SE = some evidence
- E = equivocal evidence
- NE = no evidence
Levels CE and SE are positive examples. E and NE negative examples.
Experiments are performed on rats and mice of both genders, so we
have four evidence values. An example is positive if at least one
value is SE or CE.
Some values are taken from the IJCAI-97 paper of Muggleton.
Positives (19):
- t3 (SE+3NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCACAFD4-123F-7908-7B521E4F665EFBD9
- t4 (3CE+NE) - contradicts IJCAI-97 paper and should probably be case 75-52-5 instead of 75-52-8: http://ntp.niehs.nih.gov/index.cfm?objectid=BCE49084-123F-7908-7BE127F7AF1FFBB5
- t5: paper
- t7: paper
- t8: paper
- t9 (3CE+SE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD7C6869-123F-7908-7BDEA4CFAA55CEA8
- t10: paper
- t12 (2SE+E+NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCB0ADE0-123F-7908-7BEC101C7309C4DE
- t14 (2CE+2NE) probably 111-42-2 instead of 11-42-2: http://ntp.niehs.nih.gov/index.cfm?objectid=BCC60FF1-123F-7908-7B2D579AA48DE90C
- t15: paper
- t16 (2CE+SE+E): http://ntp.niehs.nih.gov/index.cfm?objectid=BCC5D9CE-123F-7908-7B959CCE5262468A
- t18 (2SE+E+NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCA087AA-123F-7908-7B79FDFDE3CDCF87
- t19 (2CE+E+NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCAE5690-123F-7908-7B02E35E2BB57694
- t20 (2SE+E+NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCF95607-123F-7908-7B0761D3C515CC12
- t21 (CE+3NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCFCB63C-123F-7908-7BF910C2783AE9FE
- t22 (SE+3NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD8345C2-123F-7908-7BC52FEF80F110E1
- t23 (4CE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCADD2D9-123F-7908-7B5C8180FE80B22F
- t24 (CE+E): http://ntp.niehs.nih.gov/index.cfm?objectid=BCFB19FF-123F-7908-7B845E176F13E6E1
- t25 (3CE+SE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD2D2A62-123F-7908-7B0DA824E782754C
- t30 (2CE+SE+E) : http://ntp.niehs.nih.gov/index.cfm?objectid=BCB13734-123F-7908-7BEBA533E35A48B7
Negatives (10):
- t1 (4NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD9FF53C-123F-7908-7B123DAE0A25B122
- t2 (4NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCF8651E-123F-7908-7B21DD5ED83CD0FF
t4: paper
- t6: paper
- t11: paper
- t13 (4NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD136ED6-123F-7908-7B619EE79F2FD062
- t17: paper
- t26 (2E+2NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD1E6209-123F-7908-7B95EB8BAE662CE7
- t27 (E+3NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BCAC5D00-123F-7908-7BC46ECB72A6C91B
- t28 (E+3NE): http://ntp.niehs.nih.gov/index.cfm?objectid=BD34E02A-123F-7908-7BC6791917B591DF
Unclear (1):
- t29: probably a negative (see http://ntp.niehs.nih.gov/index.cfm?objectid=BD855EA1-123F-7908-7B573FC3C08188DC) but
no tests directly for this substance
The following examples are probably not part of the IJCAI PTE-2 challenge
(reports younger than 1998):
- pos: t21 (5/99), t25 (9/04), t30(10/01)
- neg: t26 (5/99), t27 (05/01), t28 (05/00), t29 (09/02)